Marfan’s syndrome is usually transmitted via an autosomal dominant gene with variable expression.
The condition may lead to progressive aortic and mitral valve regurgitation and aortic aneurysm. For those reasons the condition is of aeromedical significance and the ability to maintain a medical certificate is likely to be compromised in the long term, assuming that a certificate can be issued.
On the first occasion that an applicant presents with Marfan syndrome:
On subsequent occasions;